Neurodegenerative diseases with similar clinical features or caused by genetic workings with similar biologic features are defined "HD like" or HD related" .
Some neurodegenerative diseases of cerebellum, called Dominat Spinocerebellar Ataxia, could be associated to similar genetic features to Huntington’s Disease (expansion of DNA sections), they cause symptoms sometimes similar and unnoticeable from HD if they are in different genes. For example, the SCA17 or dentatorubral-pallidoluysian atrophy (DRPLA) could present identical symptoms and a genetic cause due to an expansion of CAG’s section, but in different genes.
These rare diseases list grows year after year and today lot of these diseases less well-know than Huntington’s Disease (HD) called SCA1, SCA2, SCA3 ecc…, they can give knowing elements to fight HD and, at the same time, they will have possible innovative future therapies efficient for Huntington’s Disease, when they will be available. Other diseases, well-known to scientific community, like atypical genetic forms of Parkinson, familiar Alzheimer’s disease or familiar dystonia (like Wilson Disease), they could represent themselves ‘connected diseases’ to Huntington’s Disease, because of their symptoms are similar to HD.
HD is considered from the Food and Drug Administration (FDA) a study model: a better knowledge of HD will allow to find the cure also for other diseases, more or less note.